Dr. Joseph Krajekian DMD, MD, FAAOMS, DABOMS
Board Certified Oral and Maxillofacial Surgeon
Regenerative Medical Technology
Biologic therapies are at the forefront of regenerative medicine, particularly in the field of oral and maxillofacial surgery (OMFS), where they are used to enhance healing and improve surgical outcomes. In the context of Virtual Surgical Planning (VSP), biologic therapies complement advanced digital workflows by promoting the body’s natural healing processes. These therapies—such as Bone Marrow Aspirate Concentrate (BMAC), Platelet-Rich Plasma (PRP), and Platelet-Rich Fibrin (PRF)—use the patient's own cells and growth factors to regenerate tissues, repair damage, and improve recovery times after surgery.
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The use of biologic therapies in OMFS offers significant advantages, such as faster recovery times, reduced risk of complications, and improved long-term results. By combining these regenerative medicine approaches with cutting-edge surgical planning and custom hardware, surgeons can provide more personalized care, ultimately achieving better outcomes for patients. The integration of biologic therapies into the surgical workflow represents a major step forward in the pursuit of minimally invasive, patient-centered care in OMFS.
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Bone Marrow Aspirate Concentrate (BMAC):
Bone Marrow Aspirate Concentrate (BMAC) is a regenerative therapy that utilizes the patient’s own bone marrow cells to promote healing and tissue regeneration in OMFS. BMAC is particularly beneficial in bone grafting and reconstructive surgeries, as it enhances bone formation, reduces recovery time, and minimizes the risk of infection. This natural approach to healing improves overall surgical outcomes and fosters faster tissue repair.
PRP (Platelet-Rich Plasma):
Platelet-Rich Plasma (PRP) therapy leverages the healing properties of the patient’s own blood to accelerate tissue regeneration. In OMFS, PRP is used to enhance healing in soft tissue and bone surgeries by delivering concentrated growth factors to the surgical site. The benefits of PRP include reduced inflammation, faster recovery, and enhanced wound healing, making it a valuable tool for improving surgical outcomes.
PRF (Platelet-Rich Fibrin):
Platelet-Rich Fibrin (PRF) is a next-generation autologous treatment used in OMFS to improve healing and tissue regeneration. Unlike PRP, PRF contains a fibrin matrix that acts as a scaffold for tissue repair, promoting sustained release of growth factors over time. PRF is particularly useful in bone grafting, tooth extraction sites, and soft tissue healing, offering enhanced recovery, reduced risk of complications, and natural tissue regeneration.
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